SANTORINI data support PCSK9i combinations for high risk patients High Lp(a) linked to plaque progression over 10 years PERI-DYS study suggests need for greater LLT intensification Latest insights from CLEAR Outcomes Phase 2b data show benefits of oral MK-0616 in hypercholesterolaemia YELLOW III supports aggressive lipid lowering to reduce plaque progression

About the PCSK9 Education and Research Forum

PCSK9 Education and Research Forum is the independent resource on PCSK9 science and its translation into critically important new treatments to lower low density lipoprotein cholesterol (LDL-C), which promise to transform the prognosis of millions of patients with hypercholesterolaemia (cholesterol disorders), accelerated atherosclerotic vascular heart disease and a high risk of premature cardiovascular (CV) death and disability.
Aims & Objectives Mission Statement Editorial Board Partnership & Outreach Forthcoming Meetings

Question of the Month

What’s new on the horizon for lipoprotein(a) therapies?

Prof Henry Ginsberg (Columbia University, New York, USA) overviews the latest news in novel Lp(a) therapies.
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Download Now: New Slide Deck Programme

Previous slide decks focused on landmark studies which used a monoclonal antibody approach to inhibit PCSK9. The next in this series discusses inclisiran, a small interfering RNA therapy, which prevents production of PCSK9 at its primary source in the liver.

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News from the Trials

Keep up to date with latest news and analyses from PCSK9 inhibitor trials.

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Trial Resources

For expert analysis and insights

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17th Virtual Closed Scientific Expert Meeting of the Editorial Board

What's new in lipoprotein(a) therapeutics?
Dr Michael Koren overviews the latest data with the siRNA olpasiran, including the OCEAN(a) trial.

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Keynote – Lipoprotein(a): “The proof of the pudding is in the trial”

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From the Editors

Lipoprotein(a) and atrial fibrillation – Is there a link?

John chapman & Henry Ginsberg Profs. John Chapman and Henry Ginsberg discuss new data implicating Lp(a) as a potential causal mediator of atrial fibrillation.