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Nabil G. Seidah Articles

PCSK9 expression in extrahepatic tissues: what is the potential relevance?

PCSK9 expression in extrahepatic tissues: what is the potential relevance?

Proprotein convertase subtilisin-kexin 9 (PCSK9), the last member of the proprotein convertase family (1) discovered in 2003, has been shown to be highly expressed in liver (2). Subsequent genetic studies showed that PCSK9 was related to the regulation of circulating low-density lipoprotein (LDL) cholesterol in…

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PCSK9: What do we still need to know about its biology and therapeutic applications

PCSK9: What do we still need to know about its biology and therapeutic applications

Dr Nabil Seidah PhD, OQ, MRSC, MC Director, Laboratory of Biochemical Neuroendocrinology

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