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Review highlights benefits of PCSK9 inhibitor therapy but notes barriers to access US NLA guidance for FH includes PCSK9 inhibitors and bempedoic acid PCSK9 inhibitors benefit high risk patients with vulnerable plaques Evolocumab may improve gut health in patients with myocardial infarction FOURIER: Evolocumab cuts MACE risk in those with obesity and ASCVD American College of Cardiology emphasises PCSK9 inhibitor role for PAD in diabetes

Jay Horton Articles

PCSK9 targeting of LDLR to degradation: SNX17, a new player

Reports from the 24th Virtual Closed Scientific Expert Meeting of the Editorial Board Professor Jay Horton Supporters of the 24th Closed Scientific Expert Meeting of the Editorial Board Principal Supporters: AstraZeneca has provided a grant towards this independent project and has had no involvement…

Posted on 1 May 2026 | Posted by Jay Horton | Posted in 24th Closed Scientific Expert Meeting of the Editorial Board

About PCSK9 Education and Research Forum

PCSK9 Education and Research Forum is a not-for-profit organisation established by leading researchers in the fields of atherosclerosis, lipids and cardiovascular disease. Our mission is to raise awareness and knowledge of the significant role played by PCSK9 in lipid metabolism and its value as a novel therapeutic target.

Editorial Policy

Unless otherwise indicated, opinions expressed in the PCSK9 Education and Research Forum are those of the contributors. All patients should discuss their medication with their healthcare professional. Although every effort is made to ensure accuracy and avoid mistakes, no liability on the part of the PCSK9 Forum, the editors or the editorial board is accepted for the consequences of any misleading or inaccurate information.

Educational Partners and Supporters

AstraZeneca has provided a grant towards this independent project and has had no involvement in its creation or organisation.