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Anne Tybjaerg-Hansen Articles

Genetics of Lp(a) and CVD

Genetics of Lp(a) and CVD

Reports from the 9th Closed Expert Meeting of the PCSK9 Education and Research Forum Professor Anne Tybjærg-Hansen 

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PlayLoss of function mutations in PCSK9: the trigger for therapeutic development

Loss of function mutations in PCSK9: the trigger for therapeutic development

Studies of mutations of PCSK9 function have identified a new therapeutic target for reducing very high levels of low density lipoprotein cholesterol (LDL-C). Professor Anne Tybjaerg-Hansen describes this opportunity.

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Mechanistic insights from PCSK9 LOF mutations

Mechanistic insights from PCSK9 LOF mutations

Mechanistic insights from PCSK9 LOF mutations with a particular focus on data from the Copenhagen studies, were discussed by Professor Anne Tybjaerg-Hansen, Rigshospitalet, Copenhagen University Hospital, and University of Copenhagen, Denmark. Seminal studies showed that carriage of LOF mutations was associated reduction in LDL cholesterol…

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