Phase 2b data show benefits of oral MK-0616 in hypercholesterolaemia YELLOW III supports aggressive lipid lowering to reduce plaque progression CLEAR Outcomes shows 13% reduction in CV events with bempedoic acid Olpasiran reduces Lp(a) irrespective of baseline Lp(a)AT-TARGET-IT: Real world data show high adherence to PCSK9 inhibitors Genetic variants in PCSK9 gene not linked to heart failure

Verve-101

A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease

Trial A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease ClinicalTrials.gov Identifier: NCT05398029 Aim To evaluate the safety of VERVE-101 administered to patients with heterozygous familial hypercholesterolaemia (HeFH), atherosclerotic cardiovascular disease (ASCVD), and uncontrolled hypercholesterolaemia. Study design Open-label, Phase 1b, single-ascending dose…

Posted on 3 August 2022 | Posted in Trials, Verve-101

About PCSK9 Education and Research Forum

PCSK9 Education and Research Forum is a not-for-profit organisation established by leading researchers in the fields of atherosclerosis, lipids and cardiovascular disease. Our mission is to raise awareness and knowledge of the significant role played by PCSK9 in lipid metabolism and its value as a novel therapeutic target.

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