VICTORION-INITIATE supports early inclisiran treatment in ASCVD LIBerate-HR: Lerodalcibep reduces LDL-C in high and very high risk CVD US patients missing out on bempedoic acid Evolocumab benefits in patients with autoimmune and inflammatory diseases CLEAR Outcomes confirms bempedoic acid benefits for recurrent CV events PCSK9i access remains challenging in USA

Verve-101

A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease

Trial A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease ClinicalTrials.gov Identifier: NCT05398029 Aim To evaluate the safety of VERVE-101 administered to patients with heterozygous familial hypercholesterolaemia (HeFH), atherosclerotic cardiovascular disease (ASCVD), and uncontrolled hypercholesterolaemia. Study design Open-label, Phase 1b, single-ascending dose…

Posted on 3 August 2022 | Posted in Trials, Verve-101

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PCSK9 Education and Research Forum is a not-for-profit organisation established by leading researchers in the fields of atherosclerosis, lipids and cardiovascular disease. Our mission is to raise awareness and knowledge of the significant role played by PCSK9 in lipid metabolism and its value as a novel therapeutic target.

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