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PCSK9 Inhibitors

PlayESC/EAS Task Force issues updated clinical guidance for PCSK9 inhibitors

ESC/EAS Task Force issues updated clinical guidance for PCSK9 inhibitors

This Task Force from the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) has considered new evidence from cardiovascular outcomes studies with evolocumab (FOURIER) and bococizumab (now terminated), new analyses and genetic studies.t Taking account of the cost of these agents, the Task…

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New network meta-analysis of PCSK9 inhibitor efficacy

New network meta-analysis of PCSK9 inhibitor efficacy

This analysis reaffirms the efficacy of PCSK9 monoclonal antibody therapy added to medium- to high-intensity statin therapy in lowering LDL cholesterol. The authors reviewed 69 trials of lipid-lowering therapies that enrolled patients requiring further LDL cholesterol reduction while on maximally tolerated medium- or high-intensity statin…

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