PACMAN-AMI: new data on lesion-level effects of lipid lowering AT-TARGET-IT shows reduced CV risk with early PCSK9i in ACS Real world ischaemic event reduction with PCSK9i mAbs Inclisiran role in plaque stabilisation Discontinuing PCSK9i leads to increased MACE V-MONO trial of inclisiran monotherapy meets primary endpoints

Paedriatic FH

Familial hypercholesterolaemia-causing mutations prevalent in ACS

According to this Spanish study, one in 10 patients aged < 65 years with an acute coronary syndrome and elevated LDL cholesterol levels has a mutation causative for familial hypercholesterolaemia (FH, inherited high cholesterol). The study assessed the prevalence of mutations in 7 genes (LDLR,…

Posted on 18 October 2017 | Posted in News

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PCSK9 Education and Research Forum is a not-for-profit organisation established by leading researchers in the fields of atherosclerosis, lipids and cardiovascular disease. Our mission is to raise awareness and knowledge of the significant role played by PCSK9 in lipid metabolism and its value as a novel therapeutic target.

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