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News

Study lays ground work for saffron as natural PCSK9 inhibitor PCSK9 inhibitors could reduce cardiac remodelling following MI PCSK9 inhibitors do not increase bleeding events after PCI Older ASCVD patients benefit from LDL-C lowering with evolocumab A critical appraisal of PCSK9 inhibitors: PCSK9 monoclonal antibodies versus small interfering RNA Evolocumab prevents carotid artery wall thickening in paediatric HeFH

Trials

ALN-PCSsc data suggest 6-month dosing

There was more news from the Phase I trial of ALN-PCSsc, an investigational RNAi therapeutic targeting PCSK9, presented at the last Latebreaker Clinical Trials session. Following initial results, presented at the European Society of Cardiology Congress, London, data reported at the American Heart Association Scientific…

Posted on 12 November 2015 | Posted in News, ALN-PCS, AHA Scientific Sessions 2015

Bococizumab: Phase II trial

Bococizumab: Phase II trial Reference: Ballantyne CM, Neutel J, Cropp A, et al. Results of bococizumab, a monoclonal antibody against proprotein convertase subtilisin/kexin type 9, from a randomized, placebo-controlled, dose-ranging study in statin-treated subjects with hypercholesterolemia. Am J Cardiol 2015; 115:1212–21. Link: http://www.ncbi.nlm.nih.gov/pubmed/25784512 Trial Bococizumab:…

Posted on 13 May 2014 | Posted in Bococizumab

About PCSK9 Education and Research Forum

PCSK9 Education and Research Forum is a not-for-profit organisation established by leading researchers in the fields of atherosclerosis, lipids and cardiovascular disease. Our mission is to raise awareness and knowledge of the significant role played by PCSK9 in lipid metabolism and its value as a novel therapeutic target.

Editorial Policy

Unless otherwise indicated, opinions expressed in the PCSK9 Education and Research Forum are those of the contributors. All patients should discuss their medication with their healthcare professional. Although every effort is made to ensure accuracy and avoid mistakes, no liability on the part of the PCSK9 Forum, the editors or the editorial board is accepted for the consequences of any misleading or inaccurate information.

Educational Partners and Supporters

AstraZeneca has provided a grant towards this independent project and has had no involvement in its creation or organisation