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Alirocumab effective against the spectrum of mutations causative for familial hypercholesterolaemia

Alirocumab effective against the spectrum of mutations causative for familial hypercholesterolaemia

Alirocumab treatment was effective in patients heterozygous for mutations in LDLR, APOB, and PCSK9 genes. This analysis investigated the efficacy of alirocumab in 1191 patients with familial hypercholesterolaemia (FH, inherited high cholesterol) included in 6 trials; 758 were treated with alirocumab. One or more specific…

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