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Nabil G. Seidah Articles

Keynote – History of PCSK9

Keynote – History of PCSK9

Reports from the 15th Virtual Closed Scientific Expert Meeting of the Editorial Board  Professor Nabil Seidah 

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PCSK9 expression in extrahepatic tissues: what is the potential relevance?

PCSK9 expression in extrahepatic tissues: what is the potential relevance?

Proprotein convertase subtilisin-kexin 9 (PCSK9), the last member of the proprotein convertase family (1) discovered in 2003, has been shown to be highly expressed in liver (2). Subsequent genetic studies showed that PCSK9 was related to the regulation of circulating low-density lipoprotein (LDL) cholesterol in…

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